In 1940 Steinbeck went on an expedition to the Gulf of California (also called The Sea of Cortez) with his friend Ed Ricketts, a marine biologist. Steinbeck shared with him a deep interest in biology. The result of this trip was a joint publication, The Sea of Cortez: A Leisurely Journal of Travel and Research. The book is in two parts. The first part narrates the voyage and records various conversations and speculations, and the second part describes the marine organisms collected by the men.

Other works include Cannery Row (1944), The Wayward Bus (1947), The Pearl (1947), Burning Bright (1950), East of Eden (1952), Sweet Thursday (1954), and The Winter of Our Discontent(1961). East of Eden is Steinbeck's longest and most ambitious work. It follows three generations of a Californian family from 1860 to the First World War. The title refers to the family strife, which parallels the conflict between the Biblical figures of Cain and Abel.
Steinbeck received the Pulitzer Prize in 1940 and the Nobel Prize for Literature in 1962. He died on December 20, 1968, and is buried in Salinas, California, the place of his birth and setting for many of his novels.

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